At a training event last week this was brought up as a possible treatment for Opiate overdose.

I have to confess to complete ignorance on this and would be grateful for others' views and experiences.

As always, many thanks in anticipation of your usual helpful answers.

George

Hi George

Two top guys in Birmingham are Dr Modern & Steve Freer
Reliable informed they've recently purchased 1500 mad squirty things !

nigel.modern@yahoo.co.uk
stevefreer4@yahoo.co.uk

My motto is : If they dont respond to the offer of free £10 rock, squirt em!

Best

Jimi ;-)

Hi george, that sounds like a great lead as it could be that nasal naloxone has finally hit the UK. It's been around in USA for a while and is effective but think there were lots of commercial obstacles. a chap called Dan Bigg used to lobby for wider use in the US, if you google him you may find more info.

hi
i have just returned from hols (sunny france) to emails from Nigel Modern which seem to suggest that doorways have been found though the brick walls which had seemed to be between us and the use of these brilliant devices.
here are the references from the bottom of his paper for a meeting to be held next week:: (which i am assuming he would not mind being posted)

As suggested above, interested people could email him for more info.. we have meetings this week in birmingham to discuss further progress i think..

""References:
1. Randomised trial of intranasal versus intramuscular naloxone in prehospital treatment for suspected opioid overdose, Anne-Maree Kelly, Debra Kerr, Paul Dietze, Ian Patrick, Tony Walker and Zeff Koutsogiannis MJA 2005; 182: 24–27
2. Out-of-hospital treatment of opioid overdoses in an urban setting., Sporer KA'Firestone J'Isaacs SM Academic emergency medicine: official journal of the Society for Academic Emergency Medicine, July 1996, vol./is. 3/7(660-7), 1069-6563
3. Intranasal administration of naloxone by paramedics. Barton ED'Ramos J'Colwell C'Benson J'Baily J'Dunn W, Prehospital Emergency Care, 01 January 2002, vol./is. 6/1(54-58), 10903127
4. The naloxone programme: Investigation of the wider use of naloxone in the prevention of overdose deaths in pre-hospital care FINAL REPORT: June 2007 Commissioned by: The National Treatment Agency for Substance Misuse, Strang, J et al
5. Prescribing Naloxone to Actively Injecting Heroin Users: A Program to Reduce Heroin Overdose Deaths, Maxwell et al Journal of Addictive Diseases, Vol. 25(3) 2006
6. Saved by the nose: Bystander-Administered Intranasal Naloxone Hydrochloride for Opioid Overdose, Doe-Simkins et al,American Journal of Public Health, May 2009, Vol 99 No 5.

Dr N Modern, reviewed May 2009 ""

Hi

Just in case anyone is wondering what we are blathering on
about,this link should show a picture of a mad spray device !

http://www.carestream.com/uplo...ice%20Literature.pdf

Jimi ;-)

Preventing overdose and saving lives

http://www.drugpolicy.org/docU...eReportMarch2009.pdf

Page 10 is a superb section highlighting legal protections.
(Good Samaritan Immunity Laws & Liability Mitigation)

The naloxone conundrum is addictive or maybe i'm just OCD !?

Jimi

Hi guys,

Anyone who wants copies of our draft documents on IN naloxone should email me on nigel.modern@yahoo.co.uk

It's a little politically sensitive locally so please, please do not distribute them or quote them extensively.

We hope to be through clinical governance in the near future.

The commonly stated argument against IN naloxone is that compared to IM it works more slowly, however the difference is not huge and 2 studies now show IN to be less likely to be associated with agitation/aggression on rousal - a factor which may make proper follow up by ambulance personnel more tricky and less likely to happen.

What makes me most comfortable with accepting IN with its possibly slightly slower but probably no less effective response is that IN is more acceptable to users, police, the public, hostels etc etc. It's usually not a choice between IM or IN naloxone for peer or untrained staff use but IN or nothing.

Nigel